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Product details

EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL

Catalog number BNC683074-100

Price for BNC683074-100

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Size / count 1x 100 µL

About this product

This antibody recognises human prolyl hydroxylase 2 (PHD2), a 46 kDa enzyme expressed abundantly in all tissues with the highest expression in testis. Hypoxia inducible factor-1 (HIF-1) is a transcriptional complex, consisting of an alpha and beta subunit, which plays a key role in coordinating the cellular response to hypoxia. During normal oxygen conditions, the alpha subunit of HIF-1 is rapidly degraded, however when hypoxia occurs this degradation is suppressed and HIF-1 activates the transcription of various genes important for survival and adaptation to hypoxia. Prolyl hydroxylase 2 catalyses the hydroxylation of specific prolyl residues within the HIF-1 alpha subunit, thereby targeting this subunit for degradation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC683074-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Chromosome 1 Open Reading Frame 12 (C1ORF12) ; DKFZp761F179; ECYT3; Egl 9 family hypoxia inducible factor 1; Egl nine homolog 1; Egln1; HIF Prolyl Hydroxylase 2 (HIF PH2) ; HIFPH2; HPH2; Hypoxia inducible factor prolyl hydroxylase 2; ORF13; P4H2; PhD2; PNAS 118; PNAS 137; Prolyl hydroxylase domain-containing protein 2; SM20; Zinc finger MYND domain containing protein 6 (ZMYND6)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
EGLN1
Gene ID
54583
NCBI Gene ID
444450
UniProt
Q9GZT9
Swiss Prot
Q9GZT9
Host
Mouse
Species Reactivity
Human
Reactivity
EGLN1|PHD2
Immunogen
Residues 1-24 of PHD2
Target Antigen
EGLN1 | PHD2
Clonality
Monoclonal
Clone
366G/76/3
Type
Primary
Source
Animal
Origin
Animal
Positive Control
MCF7 cells. Brain or adrenal gland.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
46 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL?

The catalog number for EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL is BNC683074-100.

What sizes are available for EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL?

EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL in stock?

EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL?

EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL?

The safety data sheet for EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e104af9/msds/bnc683074-100.pdf.

What is EGLN1 / PHD2 (366G/76/3), CF568 conjugate, 0.1mg/mL used for?

This antibody recognises human prolyl hydroxylase 2 (PHD2), a 46 kDa enzyme expressed abundantly in all tissues with the highest expression in testis. Hypoxia inducible factor-1 (HIF-1) is a transcriptional complex, consisting of an alpha and beta subunit, which plays a key role in coordinating the

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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