APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL

Catalog number BNC043076-500

Price for BNC043076-500

Size / count 1x 500 µL

About this product

Adenomatous Polyposis Coli (APC) is a protein with many cellular functions. It is a tumor suppressor and negative regulator of Wnt signaling. APC has roles in cell adhesion and cell migration. Mutations in APC are assuciated with several diseases. The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner's syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC043076-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Adenomatous Polyposis Coli; APC; CC1; Deleted in polyposis 2.5; Protein Phosphatase 1, Regulatory Subunit 46; DP2; DP3
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: APC
Gene ID: 324
NCBI Gene ID: 158932
UniProt: P25054
Swiss Prot: P25054
Host: Mouse
Species Reactivity: Human
Reactivity: Adenomatous Polyposis Coli
Immunogen: Recombinant fragment of human APC protein (around aa 1-433)
Target Antigen: Adenomatous Polyposis Coli
Clonality: Monoclonal
Clone: ALi 12-28
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (published) |IHC, frozen (published) |IP (published) |WB (published)
Positive Control: COLO 320DM whole cell lysate. HCT116 cells. Tonsil, placenta, breast or colon.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 66 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1998) 95:3122-3127. (WB, IF, epitope mapping) EMBO Rep (2005) 6:184-190. (IF) BMC Cell Biol (2006) 7: 3. (IF, WB) Int J Mol Med (2008) 21:19-31. (IHC, frozen) J Biol Chem (2012) 287(34): 28552-28563. (IP, WB)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL?

The catalog number for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL is BNC043076-500.

What sizes are available for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL?

APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL in stock?

APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL?

APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL?

The safety data sheet for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101d03/msds/bnc043076-500.pdf.

What is APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF405S conjugate, 0.1mg/mL used for?

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.