APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL

Catalog number BNC403076-100

Price for BNC403076-100

Size / count 1x 100 µL

About this product

Adenomatous Polyposis Coli (APC) is a protein with many cellular functions. It is a tumor suppressor and negative regulator of Wnt signaling. APC has roles in cell adhesion and cell migration. Mutations in APC are assuciated with several diseases. The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner's syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC403076-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Adenomatous Polyposis Coli; APC; CC1; Deleted in polyposis 2.5; Protein Phosphatase 1, Regulatory Subunit 46; DP2; DP3
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: APC
Gene ID: 324
NCBI Gene ID: 158932
UniProt: P25054
Swiss Prot: P25054
Host: Mouse
Species Reactivity: Human
Reactivity: Adenomatous Polyposis Coli
Immunogen: Recombinant fragment of human APC protein (around aa 1-433)
Target Antigen: Adenomatous Polyposis Coli
Clonality: Monoclonal
Clone: ALi 12-28
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (published) |IHC, frozen (published) |IP (published) |WB (published)
Positive Control: COLO 320DM whole cell lysate. HCT116 cells. Tonsil, placenta, breast or colon.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 66 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1998) 95:3122-3127. (WB, IF, epitope mapping) EMBO Rep (2005) 6:184-190. (IF) BMC Cell Biol (2006) 7: 3. (IF, WB) Int J Mol Med (2008) 21:19-31. (IHC, frozen) J Biol Chem (2012) 287(34): 28552-28563. (IP, WB)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL?

The catalog number for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL is BNC403076-100.

What sizes are available for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL?

APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL in stock?

APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL?

APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL?

The safety data sheet for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e10045c/msds/bnc403076-100.pdf.

What is APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF640R conjugate, 0.1mg/mL used for?

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.