MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL

Catalog number BNC403086-100

Price for BNC403086-100

Size / count 1x 100 µL

About this product

The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family, GTBP (also designated MSH6), is an MSH2-related protein that binds to DNA containing G/T mismatches. Findings suggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC403086-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: DNA mismatch repair protein Msh6; G/T mismatch-binding protein; GTBP; GTMBP; hMSH6; HNPCC5; HSAP; MSH6; mutS (E. coli) homolog 6; MutS alpha 160kDa subunit; MutS-alpha 160kDa subunit; p160; Sperm associated protein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MSH6
Gene ID: 2956
NCBI Gene ID: 445052
UniProt: P52701
Swiss Prot: P52701
Host: Mouse
Species Reactivity: Human
Reactivity: MSH6
Immunogen: Recombinant fragment of human MSH6 protein (around aa 374-540) (exact sequence is proprietary)
Target Antigen: MSH6
Clonality: Monoclonal
Clone: MSH6/3086
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control: HCT116 or HeLa cell lysate (WB). Human colon carcinoma (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 163 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL?

The catalog number for MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL is BNC403086-100.

What sizes are available for MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL?

MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL in stock?

MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL?

MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL?

The safety data sheet for MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ad061270361e1088c5/msds/bnc403086-100.pdf.

What is MSH6 (DNA Mismatch Repair Protein) (MSH6/3086), CF640R conjugate, 0.1mg/mL used for?

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.