MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL

Catalog number BNC683091-500

Price for BNC683091-500

Size / count 1x 500 µL

About this product

The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family, GTBP (also designated MSH6), is an MSH2-related protein that binds to DNA containing G/T mismatches. Findings suggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC683091-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: DNA mismatch repair protein Msh6; G/T mismatch-binding protein; GTBP; GTMBP; hMSH6; HNPCC5; HSAP; MSH6; mutS (E. coli) homolog 6; MutS alpha 160kDa subunit; MutS-alpha 160kDa subunit; p160; Sperm associated protein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MSH6
Gene ID: 2956
NCBI Gene ID: 445052
UniProt: P52701
Swiss Prot: P52701
Host: Mouse
Species Reactivity: Human
Reactivity: MSH6
Immunogen: Recombinant fragment of human MSH6 protein (around aa 374-540) (exact sequence is proprietary)
Target Antigen: MSH6
Clonality: Monoclonal
Clone: MSH6/3091
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control: HCT116, MCF-7 cells, Human colon carcinoma (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 163 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL?

The catalog number for MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL is BNC683091-500.

What sizes are available for MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL?

MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL in stock?

MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL?

MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL?

The safety data sheet for MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a9061270361e106f3b/msds/bnc683091-500.pdf.

What is MSH6 (DNA Mismatch Repair Protein) (MSH6/3091), CF568 conjugate, 0.1mg/mL used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.