• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL

Catalog number BNC943136-100

Price for BNC943136-100

Sign In for Pricing

Size / count 1x 100 µL

About this product

Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2 -dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG) . BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC943136-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
C-type lectin domain family 4 member K; CD207; CLEC4K; Langerhans cell specific c type lectin; Langerin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD207
Gene ID
50489
NCBI Gene ID
199731
UniProt
Q9UJ71
Swiss Prot
Q9UJ71
Host
Rabbit
Species Reactivity
Human
Reactivity
CD207|Langerin
Immunogen
Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
Target Antigen
CD207 | Langerin
Clonality
Recombinant Monoclonal
Clone
LGRN/3136R
Type
Primary
Source
Animal
Origin
Animal
Positive Control
HeLa or A549 cells. Skin.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
48 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL?

The catalog number for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL is BNC943136-100.

What sizes are available for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL?

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL in stock?

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL?

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a2061270361e10470e/msds/bnc943136-100.pdf.

What is Langerin / CD207 (Marker of Langerhans Cells) (LGRN/3136R), CF594 conjugate, 0.1mg/mL used for?

Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

You Might Also Like
CD31 / PECAM-1 (158-2B3), CF488A conjugate, 0.1mg/mL
CD31 / PECAM-1 (158-2B3), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880352-100
Cytokeratin 8/18 (C-51), CF405S conjugate, 0.1mg/mL
Cytokeratin 8/18 (C-51), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040034-100
MUC2 (CCP58), CF647 conjugate, 0.1mg/mL
MUC2 (CCP58), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470032-500
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF640R conjugate, 0.1mg/mL
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC401429-100
CD46 (122.2), CF740 conjugate, 0.1mg/mL
CD46 (122.2), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740175-500
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF647 conjugate, 0.1mg/mL
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471429-100
Fibronectin (TV-1), CF568 conjugate, 0.1mg/mL
Fibronectin (TV-1), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680029-500
Villin (GI-Mucosal & Urogenital Brush Border Marker) (VIL1/1325), CF647 conjugate, 0.1mg/mL
Villin (GI-Mucosal & Urogenital Brush Border Marker) (VIL1/1325), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471325-100