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Product details

MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL

Catalog number BNCB3179-100

Price for BNCB3179-100

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Size / count 1x 100 µL

About this product

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB3179-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cell Surface Glycoprotein MUC18; Cell Surface Glycoprotein P1H12; Gicerin; Melanoma Adhesion Molecule (MCAM) ; Melanoma Associated Glycoprotein MUC18; Melanoma Cell Adhesion Molecule; Melanoma-associated Antigen A32; Mel-CAM; S-endo 1 Endothelial-associated Antigen; Sendo1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MCAM
Gene ID
4162
NCBI Gene ID
599039
UniProt
P43121
Swiss Prot
P43121
Host
Mouse
Species Reactivity
Human
Reactivity
CD146|MCAM|MUC18
Immunogen
Recombinant human MCAM protein
Target Antigen
CD146 | MCAM | MUC18
Clonality
Monoclonal
Clone
MCAM/3179
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Cancer, Mucins
Positive Control
A-375, HUV-EC or HeLa cells. Tonsil or Melanoma (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
130 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2c, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL?

The catalog number for MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL is BNCB3179-100.

What sizes are available for MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL?

MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL in stock?

MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL?

MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL?

The safety data sheet for MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a2061270361e1043f0/msds/bncb3179-100.pdf.

What is MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 (MCAM/3179), Biotin conjugate, 0.1mg/mL used for?

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metast

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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