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Product details

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL

Catalog number BNC883190-100

Price for BNC883190-100

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Size / count 1x 100 µL

About this product

DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC883190-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD209; CDSIGN; CIRE; CLEC4L; DC-SIGN; DC-SIGN1; DCSIGN; Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1; HIV GP120 Binding Protein; SIGN-R1; SIGNR5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD209
Gene ID
30835
NCBI Gene ID
278694
UniProt
Q9NNX6
Swiss Prot
Q9NNX6
Host
Mouse
Species Reactivity
Human
Reactivity
CD209|DC-SIGN
Immunogen
Recombinant human CD209 protein fragment (exact sequence is proprietary)
Target Antigen
CD209 | DC-SIGN
Clonality
Recombinant Monoclonal
Clone
RC209/1781
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
THP-1 or HeLa cells (IF/FACS). Human liver or spleen lysate (WB). Human small intestine (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
45 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL?

The catalog number for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL is BNC883190-100.

What sizes are available for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL?

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL in stock?

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL?

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL?

The safety data sheet for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a5061270361e1055c5/msds/bnc883190-100.pdf.

What is CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (rC209/1781), CF488A conjugate, 0.1mg/mL used for?

DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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