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Product details

Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL

Catalog number BNC403194-100

Price for BNC403194-100

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Size / count 1x 100 µL

About this product

Recognizes a protein of 30 kDa which is identified as Prohibitin, an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although prohibitin mRNA and protein expression occurs throughout the cell cycle, maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. Prohibitin is an ideal mitochondrial marker. It shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC403194-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Epididymis luminal protein 215; Epididymis secretory sperm binding protein Li 54e; HEL 215; HEL S 54e; PHB; PHB1; Prohibitin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PHB
Gene ID
5245
NCBI Gene ID
514303
UniProt
P35232
Swiss Prot
P35232
Host
Mouse
Species Reactivity
Human
Reactivity
Prohibitin
Immunogen
Recombinant human PHB protein fragment (aa167-261) (exact sequence is proprietary)
Target Antigen
Prohibitin
Clonality
Monoclonal
Clone
PHB/3194
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control
Ramos, Jurkat, HEK293, K562, HepG2, A431 or MCF-7 cells (IF). Liver, Kidney, Heart or Endometrium (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~30 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL?

The catalog number for Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL is BNC403194-100.

What sizes are available for Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL?

Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL in stock?

Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL?

Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b8061270361e10c02e/msds/bnc403194-100.pdf.

What is Prohibitin (Mitochondrial Marker) (PHB/3194), CF640R conjugate, 0.1mg/mL used for?

Recognizes a protein of 30 kDa which is identified as Prohibitin, an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although prohibitin mRNA and protein expression occurs throughout the cell cycle, maximum levels are detec

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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