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Product details

PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL

Catalog number BNC683196-500

Price for BNC683196-500

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Size / count 1x 500 µL

About this product

Recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC683196-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Paired box 8; Paired box gene 8; paired box homeotic gene 8; Paired box protein Pax-8; Paired domain gene 8; PAX8
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PAX8
Gene ID
7849
NCBI Gene ID
469728
UniProt
Q06710
Swiss Prot
Q06710
Host
Mouse
Species Reactivity
Human
Reactivity
PAX8
Immunogen
Recombinant fragment (around aa 60-261) of human PAX8 protein (exact sequence is proprietary)
Target Antigen
PAX8
Clonality
Recombinant Monoclonal
Clone
RPAX8/1492
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Raji cells. Renal Cell Carcinoma (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
62 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL?

The catalog number for PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL is BNC683196-500.

What sizes are available for PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL?

PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL in stock?

PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL?

PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL?

The safety data sheet for PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101cfd/msds/bnc683196-500.pdf.

What is PAX8 (Renal Cell Marker) (rPAX8/1492), CF568 conjugate, 0.1mg/mL used for?

Recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysge

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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