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Product details
Catalog number BNC403232-500
Price for BNC403232-500
Size / count 1x 500 µL
Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA) . Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS) . Cox-1 is constitutively expressed in most tissues and is thought to serve in general housekeeping functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs. COX2 expression is significantly increased in 85-90% of human colorectal adenocarcinomas whereas levels of COX-1 are not changed. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Cycloxygenase-2 (COX-2) (COX2/3232R), CF640R conjugate, 0.1mg/mL is BNC403232-500.
Cycloxygenase-2 (COX-2) (COX2/3232R), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
Cycloxygenase-2 (COX-2) (COX2/3232R), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Cycloxygenase-2 (COX-2) (COX2/3232R), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Cycloxygenase-2 (COX-2) (COX2/3232R), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Cycloxygenase-2 (COX-2) (COX2/3232R), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b3061270361e10a4cc/msds/bnc403232-500.pdf.
Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
