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Product details

Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL

Catalog number BNC683232-500

Price for BNC683232-500

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Size / count 1x 500 µL

About this product

Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA) . Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS) . Cox-1 is constitutively expressed in most tissues and is thought to serve in general housekeeping functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs. COX2 expression is significantly increased in 85-90% of human colorectal adenocarcinomas whereas levels of COX-1 are not changed. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC683232-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase; GRIPGHS; Macrophage activation-associated marker protein P71/73; PES-2; PGG/HS; PGHS-2; Prostaglandin endoperoxide synthase 2; Prostaglandin endoperoxide synthase 2 (PTGS2) ; TIS10
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PTGS2
Gene ID
5743
NCBI Gene ID
196384
UniProt
P35354
Swiss Prot
P35354
Host
Rabbit
Species Reactivity
Human
Reactivity
Cycloxygenase-2
Immunogen
Recombinant human COX2 protein fragment (around aa 442-572) (exact sequence is proprietary)
Target Antigen
Cycloxygenase-2
Clonality
Recombinant Monoclonal
Clone
COX2/3232R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Human colon or lung carcinoma tissue (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
70-72 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL?

The catalog number for Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL is BNC683232-500.

What sizes are available for Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL?

Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL in stock?

Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL?

Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a7061270361e106386/msds/bnc683232-500.pdf.

What is Cycloxygenase-2 (COX-2) (COX2/3232R), CF568 conjugate, 0.1mg/mL used for?

Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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