Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL

Catalog number BNC473244-100

Price for BNC473244-100

Size / count 1x 100 µL

About this product

Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2. 4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin represents approximately 0. 002% of total striated muscle protein and localizes to triadic junctions in skeletal muscle, where it is thought to influence calcium ion homeostasis and force transmission. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC473244-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BMD; CMD3B; Duchenne muscular dystrophy (DMD) ; Dystrophin; Muscular dystrophy Duchenne and Becker types
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: DMD
Gene ID: 1756
NCBI Gene ID: 495912
UniProt: P11532
Swiss Prot: P11532
Host: Mouse
Species Reactivity: Human
Reactivity: Dystrophin
Immunogen: A recombinant fragment (around aa 114-263) of human DMD protein (exact sequence is proprietary)
Target Antigen: Dystrophin
Clonality: Monoclonal
Clone: DMD/3244
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human skeletal muscle and heart muscle tissues (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 427 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL?

The catalog number for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL is BNC473244-100.

What sizes are available for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL?

Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL in stock?

Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL?

Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102d3f/msds/bnc473244-100.pdf.

What is Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3244), CF647 conjugate, 0.1mg/mL used for?

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.