Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL

Catalog number BNC043245-100

Price for BNC043245-100

Size / count 1x 100 µL

About this product

Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2. 4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin represents approximately 0. 002% of total striated muscle protein and localizes to triadic junctions in skeletal muscle, where it is thought to influence calcium ion homeostasis and force transmission. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC043245-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BMD; CMD3B; Duchenne muscular dystrophy (DMD) ; Dystrophin; Muscular dystrophy Duchenne and Becker types
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: DMD
Gene ID: 1756
NCBI Gene ID: 495912
UniProt: P11532
Swiss Prot: P11532
Host: Mouse
Species Reactivity: Human
Reactivity: Dystrophin
Immunogen: A recombinant fragment (around aa 114-263) of human DMD protein (exact sequence is proprietary)
Target Antigen: Dystrophin
Clonality: Monoclonal
Clone: DMD/3245
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human skeletal muscle and heart muscle tissues (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 427 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL?

The catalog number for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL is BNC043245-100.

What sizes are available for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL?

Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL in stock?

Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL?

Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b0061270361e109806/msds/bnc043245-100.pdf.

What is Dystrophin (DMD) (Marker of Duchenne and Becker Muscular Dystrophy) (DMD/3245), CF405S conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.