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Product details

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL

Catalog number BNC043247-100

Price for BNC043247-100

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Size / count 1x 100 µL

About this product

Recognizes a protein of 140 kDa, which is identified as the complement receptor 2 (CR2) or CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC043247-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD21; Complement C3d receptor (C3DR) ; Complement Receptor type 2 (CR2) ; CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; SLEB9
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CR2
Gene ID
1380
NCBI Gene ID
445757
UniProt
P20023
Swiss Prot
P20023
Host
Mouse
Species Reactivity
Human
Reactivity
CD21
Immunogen
Recombinant fragment (around aa 142-240) of human CR2 (CD21) protein (exact sequence is proprietary)
Target Antigen
CD21
Clonality
Monoclonal
Clone
CR2/3247
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Raji or WEHI-231 cells. Tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
140 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL?

The catalog number for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL is BNC043247-100.

What sizes are available for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL?

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL in stock?

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL?

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL?

The safety data sheet for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e104ab3/msds/bnc043247-100.pdf.

What is CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/3247), CF405S conjugate, 0.1mg/mL used for?

Recognizes a protein of 140 kDa, which is identified as the complement receptor 2 (CR2) or CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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