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Product details

CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL

Catalog number BNC403249-500

Price for BNC403249-500

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Size / count 1x 500 µL

About this product

At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC403249-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cortical thymocyte antigen CD1A; Epidermal dendritic cell marker CD1a; FCB6; HTA1; T cell surface antigen T6 / Leu 6; T-Cell Surface Glycoprotein CD1A
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD1A
Gene ID
909
NCBI Gene ID
1309
UniProt
P06126
Swiss Prot
P06126
Host
Mouse
Species Reactivity
Human
Reactivity
CD1a|HTA1
Immunogen
Recombinant fragment (around aa43-173) of human CD1A protein (exact sequence is proprietary)
Target Antigen
CD1a | HTA1
Clonality
Monoclonal
Clone
C1A/3249
Type
Primary
Source
Animal
Origin
Animal
Positive Control
MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node or skin.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
49 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL?

The catalog number for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL is BNC403249-500.

What sizes are available for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL?

CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL in stock?

CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL?

CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL?

The safety data sheet for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a8061270361e106a72/msds/bnc403249-500.pdf.

What is CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF640R conjugate, 0.1mg/mL used for?

At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein,

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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