CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL

Catalog number BNC683249-500

Price for BNC683249-500

Size / count 1x 500 µL

About this product

At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC683249-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Cortical thymocyte antigen CD1A; Epidermal dendritic cell marker CD1a; FCB6; HTA1; T cell surface antigen T6 / Leu 6; T-Cell Surface Glycoprotein CD1A
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD1A
Gene ID: 909
NCBI Gene ID: 1309
UniProt: P06126
Swiss Prot: P06126
Host: Mouse
Species Reactivity: Human
Reactivity: CD1a|HTA1
Immunogen: Recombinant fragment (around aa43-173) of human CD1A protein (exact sequence is proprietary)
Target Antigen: CD1a | HTA1
Clonality: Monoclonal
Clone: C1A/3249
Type: Primary
Source: Animal
Origin: Animal
Positive Control: MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node or skin.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 49 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL?

The catalog number for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL is BNC683249-500.

What sizes are available for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL?

CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL in stock?

CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL?

CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL?

The safety data sheet for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e101734/msds/bnc683249-500.pdf.

What is CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/3249), CF568 conjugate, 0.1mg/mL used for?

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.