E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL

Catalog number BNC683256-100

Price for BNC683256-100

Size / count 1x 100 µL

About this product

Recognizes a protein of 120-80 kDa, identified as E-cadherin. Cadherins comprise a family of Ca2 -dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as -catenin, to regulate cadherin function. E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combination with p120 Catenin, it is useful for the differentiation between ductal (E-cadherin) and lobular (E-cadherin -) breast carcinomas. It may also help in diagnosis of mesothelioma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC683256-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Arc 1; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CDHE; E-Cad/CTF3; E-cadherin; ECAD; Epithelial cadherin; epithelial calcium dependent adhesion protein; Liver cell adhesion molecule (LCAM) ; Uvomorulin (UVO)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CDH1
Gene ID: 999
NCBI Gene ID: 461086
UniProt: P12830
Swiss Prot: P12830
Host: Mouse
Species Reactivity: Human
Reactivity: CD324|E-Cadherin
Immunogen: Recombinant fragment of human CDH1 protein (around aa 567-691) (exact sequence is proprietary)
Target Antigen: CD324 | E-Cadherin
Clonality: Monoclonal
Clone: CDH1/3256
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IHC, FFPE (verified)
Positive Control: MCF-7, LS174T, Raji, HT29 or SK-BR3 cells. Prostate or Colon carcinomas.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 120-80 kDa (Mature) ; 135 kDa (Precursor)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL?

The catalog number for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL is BNC683256-100.

What sizes are available for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL?

E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL in stock?

E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL?

E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL?

The safety data sheet for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e10175a/msds/bnc683256-100.pdf.

What is E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/3256), CF568 conjugate, 0.1mg/mL used for?

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.