ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL

Catalog number BNUB3260-100

Price for BNUB3260-100

Size / count 1x 100 µL

About this product

This MAb recognizes a protein of 36 kDa, identified as ICOS-L. It is a ligand for the ICOS receptor that initiates T and B cell proliferation and cytokine secretion. ICOS-L interactions play an essential role in T cell-dependent B cell activation in peripheral lymphoid organs such as spleen and lymph nodes. ICOS-L protein is present in myeloid leukocytes, and by Northern blot there are 2. 4, 3. 0, and 7. 0 kb transcripts in brain, heart, kidney, and liver, with lower expression in colon and thymus, and a 1. 1 kb transcript in leukocytes. Tumor necrosis factor alpha (TNF), granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4) enhance its expression. LPS-induced up-regulation of ICOS-L is dependent on the MyD88-dependent signaling pathway. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB3260-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: B7 homolog 2 (B7H2) ; B7 like protein Gl50; B7 related protein 1 (B7RP1) ; CD275; CD275 antigen; GL50; ICOS LG; ICOS ligand (ICOSL) ; Inducible T cell co stimulator ligand; LICOS; Transmembrane protein B7 H2 ICOS ligand
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ICOSLG
Gene ID: 23308
NCBI Gene ID: 14155
UniProt: O75144
Swiss Prot: O75144
Host: Mouse
Species Reactivity: Human
Reactivity: B7RP-1|ICOS Ligand|ICOS-L
Immunogen: Recombinant fragment of human ICOSLG (B7RP-1) protein (around aa 23-149) (exact sequence is proprietary)
Target Antigen: B7RP-1 | ICOS Ligand | ICOS-L
Clonality: Monoclonal
Clone: ICOSL/3260
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: HL60, HuT78 and HUVEC cells. Prostate or Colon Carcinoma.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 36 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL?

The catalog number for ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL is BNUB3260-100.

What sizes are available for ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL?

ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL in stock?

ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL?

ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL?

Estimated delivery time for ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL?

The safety data sheet for ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102600/msds/bnub3260-100.pdf.

What is ICOS-L / ICOS Ligand / B7RP-1 (Immuno-Oncology Target) (ICOSL/3260), 0.2mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.