Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL — image 1 of 4

Product details

Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL

Catalog number BNC473269-500

Price for BNC473269-500

Size / count 1x 500 µL

About this product

CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for prostate adenocarcinoma, and cancers of the lung, stomach, breast, and brain. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC473269-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD105; END; Endoglin; Eng; HHT1; S-endoglin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ENG
Gene ID: 2022
NCBI Gene ID: 76753
UniProt: P17813
Swiss Prot: P17813
Host: Mouse
Species Reactivity: Human
Reactivity: CD105|Endoglin
Immunogen: Recombinant human Endoglin protein fragment (aa74-251) (exact sequence is proprietary)
Target Antigen: CD105 | Endoglin
Clonality: Monoclonal
Clone: ENG/3269
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: HeLa, A431 and HL-60 cells. Colon.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 84 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL?

The catalog number for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL is BNC473269-500.

What sizes are available for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL?

Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL in stock?

Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL?

Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102b0f/msds/bnc473269-500.pdf.

What is Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), CF647 conjugate, 0.1mg/mL used for?

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.