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Product details

Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL

Catalog number BNCB3269-100

Price for BNCB3269-100

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Size / count 1x 100 µL

About this product

CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for prostate adenocarcinoma, and cancers of the lung, stomach, breast, and brain. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB3269-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD105; END; Endoglin; Eng; HHT1; S-endoglin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ENG
Gene ID
2022
NCBI Gene ID
76753
UniProt
P17813
Swiss Prot
P17813
Host
Mouse
Species Reactivity
Human
Reactivity
CD105|Endoglin
Immunogen
Recombinant human Endoglin protein fragment (aa74-251) (exact sequence is proprietary)
Target Antigen
CD105 | Endoglin
Clonality
Monoclonal
Clone
ENG/3269
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer
Positive Control
HeLa, A431 and HL-60 cells. Colon.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
84 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL?

The catalog number for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL is BNCB3269-100.

What sizes are available for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL?

Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL in stock?

Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL?

Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e101484/msds/bncb3269-100.pdf.

What is Endoglin / CD105 (Angiogenesis Marker) (ENG/3269), Biotin conjugate, 0.1mg/mL used for?

CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system a

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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