Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL

Catalog number BNC403275-500

Price for BNC403275-500

Size / count 1x 500 µL

About this product

Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively) . Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC403275-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Cathepsin D; CTSD; Lysosomal aspartyl peptidase
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CTSD
Gene ID: 1509
NCBI Gene ID: 654447
UniProt: P07339
Swiss Prot: P07339
Host: Mouse
Species Reactivity: Human
Reactivity: Cathepsin D
Immunogen: Recombinant fragment of human Cathepsin D protein (around aa 104-250) (exact sequence is proprietary)
Target Antigen: Cathepsin D
Clonality: Monoclonal
Clone: CTSD/3275
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: MCF-7, K-562, A431 or SK-BR3 cells. Kidney, liver, lung or breast.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 46 kDa (Procathepsin D) ; 28 kDa (Cathepsin D)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL?

The catalog number for Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL is BNC403275-500.

What sizes are available for Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL?

Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL in stock?

Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL?

Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101fc0/msds/bnc403275-500.pdf.

What is Cathepsin D (Tumor Marker) (CTSD/3275), CF640R conjugate, 0.1mg/mL used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.