Product details
Catalog number BNC883275-500
Price for BNC883275-500
Size / count 1x 500 µL
Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively) . Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Cathepsin D (Tumor Marker) (CTSD/3275), CF488A conjugate, 0.1mg/mL is BNC883275-500.
Cathepsin D (Tumor Marker) (CTSD/3275), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
Cathepsin D (Tumor Marker) (CTSD/3275), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Cathepsin D (Tumor Marker) (CTSD/3275), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/3275), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Cathepsin D (Tumor Marker) (CTSD/3275), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e10283a/msds/bnc883275-500.pdf.
Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunit
Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.