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Product details

Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL

Catalog number BNC043276-500

Price for BNC043276-500

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Size / count 1x 500 µL

About this product

Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively) . Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC043276-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cathepsin D; CTSD; Lysosomal aspartyl peptidase
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CTSD
Gene ID
1509
NCBI Gene ID
654447
UniProt
P07339
Swiss Prot
P07339
Host
Mouse
Species Reactivity
Human
Reactivity
Cathepsin D
Immunogen
Recombinant fragment of human Cathepsin D protein (around aa 104-250) (exact sequence is proprietary)
Target Antigen
Cathepsin D
Clonality
Monoclonal
Clone
CTSD/3276
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control
MCF-7, K-562, A431 or SK-BR3 cells. Kidney, liver, lung or breast.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
46 kDa (Procathepsin D) ; 28 kDa (Cathepsin D)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL?

The catalog number for Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL is BNC043276-500.

What sizes are available for Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL?

Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL in stock?

Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL?

Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102af6/msds/bnc043276-500.pdf.

What is Cathepsin D (Tumor Marker) (CTSD/3276), CF405S conjugate, 0.1mg/mL used for?

Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunit

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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