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Product details

Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL

Catalog number BNCB3276-100

Price for BNCB3276-100

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Size / count 1x 100 µL

About this product

Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively) . Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB3276-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cathepsin D; CTSD; Lysosomal aspartyl peptidase
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CTSD
Gene ID
1509
NCBI Gene ID
654447
UniProt
P07339
Swiss Prot
P07339
Host
Mouse
Species Reactivity
Human
Reactivity
Cathepsin D
Immunogen
Recombinant fragment of human Cathepsin D protein (around aa 104-250) (exact sequence is proprietary)
Target Antigen
Cathepsin D
Clonality
Monoclonal
Clone
CTSD/3276
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control
MCF-7, K-562, A431 or SK-BR3 cells. Kidney, liver, lung or breast.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
46 kDa (Procathepsin D) ; 28 kDa (Cathepsin D)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL?

The catalog number for Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL is BNCB3276-100.

What sizes are available for Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL?

Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL in stock?

Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL?

Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a2061270361e1043e1/msds/bncb3276-100.pdf.

What is Cathepsin D (Tumor Marker) (CTSD/3276), Biotin conjugate, 0.1mg/mL used for?

Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunit

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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