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Product details

Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL

Catalog number BNUM3276-50

Price for BNUM3276-50

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Size / count 1x 50 µL

About this product

Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively) . Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM3276-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cathepsin D; CTSD; Lysosomal aspartyl peptidase
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CTSD
Gene ID
1509
NCBI Gene ID
654447
UniProt
P07339
Swiss Prot
P07339
Host
Mouse
Species Reactivity
Human
Reactivity
Cathepsin D
Immunogen
Recombinant fragment of human Cathepsin D protein (around aa 104-250) (exact sequence is proprietary)
Target Antigen
Cathepsin D
Clonality
Monoclonal
Clone
CTSD/3276
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control
MCF-7, K-562, A431 or SK-BR3 cells. Kidney, liver, lung or breast.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
46 kDa (Procathepsin D) ; 28 kDa (Cathepsin D)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL?

The catalog number for Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL is BNUM3276-50.

What sizes are available for Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL?

Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL in stock?

Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL?

Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL?

Estimated delivery time for Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL?

The safety data sheet for Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e1014ac/msds/bnum3276-50.pdf.

What is Cathepsin D (Tumor Marker) (CTSD/3276), 1mg/mL used for?

Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunit

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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