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Product details

Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL

Catalog number BNC473281-100

Price for BNC473281-100

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Size / count 1x 100 µL

About this product

Reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1) . It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC473281-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
5; 6 dihydroxyindole 2 carboxylic acid oxidase; 6-dihydroxyindole-2-carboxylic acid oxidase; Associated with iris pigmentation; CAS2; Catalase B (CATB) ; DHICA oxidase; Glycoprotein75 (GP75) ; Melanoma antigen gp75
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TYRP1
Gene ID
7306
NCBI Gene ID
270279
UniProt
P17643
Swiss Prot
P17643
Host
Mouse
Species Reactivity
Human
Reactivity
Tyrosinase Related Protein-1
Immunogen
A recombinant fragment (around aa 257-377) of human TYRP1 protein (exact sequence is proprietary)
Target Antigen
Tyrosinase Related Protein-1
Clonality
Monoclonal
Clone
TYRP1/3281
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells. Human Skin or Melanoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
75 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL?

The catalog number for Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL is BNC473281-100.

What sizes are available for Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL?

Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL in stock?

Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL?

Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02aa061270361e1071c5/msds/bnc473281-100.pdf.

What is Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) (TYRP1/3281), CF647 conjugate, 0.1mg/mL used for?

Reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1) . It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stabi

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

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