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Product details

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL

Catalog number BNC683285-100

Price for BNC683285-100

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Size / count 1x 100 µL

About this product

Recognizes a 33 kDa glycoprotein, identified as Nucleophosmin (NPM) . It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC683285-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
NO38; NPM; NPM1; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Nucleophosmin (nucleolar phosphoprotein B23 numatrin) ; Nucleophosmin; Nucleophosmin/nucleoplasmin family member 1; Numatrin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NPM1
Gene ID
4869
NCBI Gene ID
557550
UniProt
P06748
Swiss Prot
P06748
Host
Mouse
Species Reactivity
Human
Reactivity
Nucleophosmin
Immunogen
Recombinant human NPM1 protein fragment (aa185-287) (exact sequence is proprietary)
Target Antigen
Nucleophosmin
Clonality
Monoclonal
Clone
NPM1/3285
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified) |IHC, FFPE (verified)
Positive Control
K562, MCF-7, HeLa or A431 cells. Skin, Colon.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
33 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2c, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL?

The catalog number for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL is BNC683285-100.

What sizes are available for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL in stock?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e1014f0/msds/bnc683285-100.pdf.

What is Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3285), CF568 conjugate, 0.1mg/mL used for?

Recognizes a 33 kDa glycoprotein, identified as Nucleophosmin (NPM) . It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphopr

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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