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Product details

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL

Catalog number BNUM3287-50

Price for BNUM3287-50

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Size / count 1x 50 µL

About this product

Recognizes a 33 kDa glycoprotein, identified as Nucleophosmin (NPM) . It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM3287-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
NO38; NPM; NPM1; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Nucleophosmin (nucleolar phosphoprotein B23 numatrin) ; Nucleophosmin; Nucleophosmin/nucleoplasmin family member 1; Numatrin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NPM1
Gene ID
4869
NCBI Gene ID
557550
UniProt
P06748
Swiss Prot
P06748
Host
Mouse
Species Reactivity
Human
Reactivity
Nucleophosmin
Immunogen
Recombinant human NPM1 protein fragment (aa185-287) (exact sequence is proprietary)
Target Antigen
Nucleophosmin
Clonality
Monoclonal
Clone
NPM1/3287
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
MCF-7, HeLa or A431 cells. Human skin or colon tissue (IHC).
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
33 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL?

The catalog number for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL is BNUM3287-50.

What sizes are available for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL in stock?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL?

Estimated delivery time for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL?

The safety data sheet for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e1025d6/msds/bnum3287-50.pdf.

What is Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3287), 1mg/mL used for?

Recognizes a 33 kDa glycoprotein, identified as Nucleophosmin (NPM) . It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphopr

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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