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Product details

Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL

Catalog number BNC473291-500

Price for BNC473291-500

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Size / count 1x 500 µL

About this product

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC473291-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Actin binding protein; Alpha actinin skeletal muscle; isoform 2; CMD1AA; F-actin cross-linking protein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ACTN2
Gene ID
88
NCBI Gene ID
498178
UniProt
P35609
Swiss Prot
P35609
Host
Mouse
Species Reactivity
Human
Reactivity
ACTN2|Sarcomeric Actinin Alpha 2
Immunogen
A recombinantfragment (aa557-692) ofhuman ACTN2 protein (exact sequence is proprietary)
Target Antigen
ACTN2 | Sarcomeric Actinin Alpha 2
Clonality
Monoclonal
Clone
ACTN2/3291
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Skeletal orCardiac Muscle.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
103 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL?

The catalog number for Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL is BNC473291-500.

What sizes are available for Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL?

Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL in stock?

Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL?

Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b3061270361e10a456/msds/bnc473291-500.pdf.

What is Sarcomeric Actinin Alpha 2 / ACTN2 (ACTN2/3291), CF647 conjugate, 0.1mg/mL used for?

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isofo

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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