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Product details

Napsin A (Lung Adenocarcinoma Marker) (NAPSA/3308), 0.2mg/mL

Catalog number BNUB3308-500

Price for BNUB3308-500

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Size / count 1x 500 µL

About this product

Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB3308-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ASP4; Aspartyl protease 4; KAP; Kidney derived aspartic protease like protein (Kdap) ; NAP1; NAPA; Napsa; napsin A aspartic peptidase; Pronapsin A; SNAPA
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NAPSA
Gene ID
9476
NCBI Gene ID
512843
UniProt
O96009
Swiss Prot
O96009
Host
Mouse
Species Reactivity
Human
Reactivity
Napsin-A
Immunogen
Recombinant human Napsin-A protein fragment (aa189-299) (exact sequence is proprietary)
Target Antigen
Napsin-A
Clonality
Monoclonal
Clone
NAPSA/3308
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Proteases
Positive Control
Lung adenocarcinoma
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
37 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Product documents

Supporting information for this product.

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