CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL

Catalog number BNC683337-500

Price for BNC683337-500

Size / count 1x 500 µL

About this product

CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin aM combines with the Integrin '2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3) . Integrin aM/'2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. The protein CD11b has been implicated in the various adhesion-related interactions of cells such as monocytes, macrophages, natural killer (NK) cells, and granulocytes. It is part of a heterodimer that consists of CD11b and CD18. It also modulates the uptake of complement-coated particles within the cell. It is commonly used as a microglial marker in tissues derived from the nervous system. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC683337-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD18; CD49d; Cell surface glycoprotein MAC-1 subunit alpha; Complement Component Receptor 3 Alpha; CR3 Alpha Chain (CR3A) ; Integrin alpha-M; Integrin beta 2 alpha subunit; Leukocyte adhesion receptor MO1; Ly-40; MAC1A; Macrophage antigen alpha polypeptide; MO1A; Neutrophil adherence receptor alpha M subunit
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ITGAM
Gene ID: 3684
NCBI Gene ID: 172631
UniProt: P11215
Swiss Prot: P11215
Host: Mouse
Species Reactivity: Human
Reactivity: CD11b|MAC-1
Immunogen: Recombinant fragment (around aa941-1074) of human ITGAM protein (exact sequence is proprietary)
Target Antigen: CD11b | MAC-1
Clonality: Monoclonal
Clone: ITGAM/3337
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Monocytes & granulocytes. Lymph nodes, spleen and tonsil (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 95 kDa & 170 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL?

The catalog number for CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL is BNC683337-500.

What sizes are available for CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL?

CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL in stock?

CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL?

CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL?

The safety data sheet for CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a0061270361e103dcd/msds/bnc683337-500.pdf.

What is CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), CF568 conjugate, 0.1mg/mL used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.