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Product details

CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL

Catalog number BNC883338-500

Price for BNC883338-500

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Size / count 1x 500 µL

About this product

CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin aM combines with the Integrin '2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3) . Integrin aM/'2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. The protein CD11b has been implicated in the various adhesion-related interactions of cells such as monocytes, macrophages, natural killer (NK) cells, and granulocytes. It is part of a heterodimer that consists of CD11b andCD18. It also modulates the uptake of complement-coated particles within the cell. It is commonly used as a microglial marker in tissues derived from the nervous system. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC883338-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD18; CD49d; Cell surface glycoprotein MAC-1 subunit alpha; Complement Component Receptor 3 Alpha; CR3 Alpha Chain (CR3A) ; Integrin alpha-M; Integrin beta 2 alpha subunit; Leukocyte adhesion receptor MO1; Ly-40; MAC1A; Macrophage antigen alpha polypeptide; MO1A; Neutrophil adherence receptor alpha M subunit
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ITGAM
Gene ID
3684
NCBI Gene ID
172631
UniProt
P11215
Swiss Prot
P11215
Host
Mouse
Species Reactivity
Human
Reactivity
CD11b|MAC-1
Immunogen
Recombinant fragment (around aa941-1074) of human ITGAM protein (exact sequence is proprietary)
Target Antigen
CD11b | MAC-1
Clonality
Monoclonal
Clone
ITGAM/3338
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
Monocytes & granulocytes. Lymph nodes, spleen and tonsil (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
95 kDa & 170 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL?

The catalog number for CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL is BNC883338-500.

What sizes are available for CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL?

CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL in stock?

CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL?

CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL?

The safety data sheet for CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100a61/msds/bnc883338-500.pdf.

What is CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), CF488A conjugate, 0.1mg/mL used for?

CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin aM combines with the Integrin '2 to form a leukocyte-specific int

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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