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Product details

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL

Catalog number BNC403348-100

Price for BNC403348-100

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Size / count 1x 100 µL

About this product

NKX3. 1 is a prostate specific gene encoding a transcription factor that plays an important role in normal prostate development and carcinogenesis. It is a prostatic tumor suppressor gene located on chromosome 8p21. 2, which frequently undergoes a loss of heterozygosity. NKX3. 1 expression is highly restricted in prostate epithelial cells and therefore can be used as a diagnostic biomarker for prostate cancer and other metastatic lesions of prostatic origin. Furthermore, NKX3. 1 shows better sensitivity than Prostate Specific Antigen (PSA) for identifying metastatic prostatic adenocarcinoma. This suggests that immunohistochemical staining of NKX3. 1, along with other prostate-restricted markers, may be valuable for the definitive determination of prostatic origin in poorly differentiated metastatic carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC403348-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
NK3 Transcription Factor Related; Locus 1; NK Homeobox (Drosophila) ; Family 3; A; NK3 Transcription Factor Homolog A; NK Homeobox; Family 3; A; Homeobox Protein Nkx-3.1; BAPX2; NKX3
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NKX3-1
Gene ID
4824
NCBI Gene ID
55999
UniProt
Q99801
Swiss Prot
Q99801
Host
Mouse
Species Reactivity
Human
Reactivity
NKX3.1
Immunogen
Recombinantfragment (around aa 92-224) of humanNKX3.1 protein (exact sequence is proprietary)
Target Antigen
NKX3.1
Clonality
Monoclonal
Clone
NKX3.1/3348
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Highly expressed in the prostate and at a lower level in the testis.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
35 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL?

The catalog number for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL is BNC403348-100.

What sizes are available for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL in stock?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL?

The safety data sheet for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100767/msds/bnc403348-100.pdf.

What is NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL used for?

NKX3. 1 is a prostate specific gene encoding a transcription factor that plays an important role in normal prostate development and carcinogenesis. It is a prostatic tumor suppressor gene located on chromosome 8p21. 2, which frequently undergoes a loss of heterozygosity. NKX3. 1 expression is highly

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

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