NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL

Catalog number BNC403348-500

Price for BNC403348-500

Size / count 1x 500 µL

About this product

NKX3. 1 is a prostate specific gene encoding a transcription factor that plays an important role in normal prostate development and carcinogenesis. It is a prostatic tumor suppressor gene located on chromosome 8p21. 2, which frequently undergoes a loss of heterozygosity. NKX3. 1 expression is highly restricted in prostate epithelial cells and therefore can be used as a diagnostic biomarker for prostate cancer and other metastatic lesions of prostatic origin. Furthermore, NKX3. 1 shows better sensitivity than Prostate Specific Antigen (PSA) for identifying metastatic prostatic adenocarcinoma. This suggests that immunohistochemical staining of NKX3. 1, along with other prostate-restricted markers, may be valuable for the definitive determination of prostatic origin in poorly differentiated metastatic carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC403348-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: NK3 Transcription Factor Related; Locus 1; NK Homeobox (Drosophila) ; Family 3; A; NK3 Transcription Factor Homolog A; NK Homeobox; Family 3; A; Homeobox Protein Nkx-3.1; BAPX2; NKX3
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NKX3-1
Gene ID: 4824
NCBI Gene ID: 55999
UniProt: Q99801
Swiss Prot: Q99801
Host: Mouse
Species Reactivity: Human
Reactivity: NKX3.1
Immunogen: Recombinantfragment (around aa 92-224) of humanNKX3.1 protein (exact sequence is proprietary)
Target Antigen: NKX3.1
Clonality: Monoclonal
Clone: NKX3.1/3348
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Highly expressed in the prostate and at a lower level in the testis.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 35 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL?

The catalog number for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL is BNC403348-500.

What sizes are available for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL in stock?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL?

The safety data sheet for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e101188/msds/bnc403348-500.pdf.

What is NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3348), CF640R conjugate, 0.1mg/mL used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.