Product details
Catalog number BNC943350-500
Price for BNC943350-500
Size / count 1x 500 µL
NKX3. 1 is a prostate specific gene encoding a transcription factor that plays an important role in normal prostate development and carcinogenesis. It is a prostatic tumor suppressor gene located on chromosome 8p21. 2, which frequently undergoes a loss of heterozygosity. NKX3. 1 expression is highly restricted in prostate epithelial cells and therefore can be used as a diagnostic biomarker for prostate cancer and other metastatic lesions of prostatic origin. Furthermore, NKX3. 1 shows better sensitivity than Prostate Specific Antigen (PSA) for identifying metastatic prostatic adenocarcinoma. This suggests that immunohistochemical staining of NKX3. 1, along with other prostate-restricted markers, may be valuable for the definitive determination of prostatic origin in poorly differentiated metastatic carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3350), CF594 conjugate, 0.1mg/mL is BNC943350-500.
NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3350), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3350), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3350), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3350), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3350), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e0ffead/msds/bnc943350-500.pdf.
NKX3. 1 is a prostate specific gene encoding a transcription factor that plays an important role in normal prostate development and carcinogenesis. It is a prostatic tumor suppressor gene located on chromosome 8p21. 2, which frequently undergoes a loss of heterozygosity. NKX3. 1 expression is highly
A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.