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Product details
Catalog number BNC473351-100
Price for BNC473351-100
Size / count 1x 100 µL
Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous and chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin I and spectrin I are present in erythrocytes, whereas spectrin II (also designated fodrin) and spectrin II (also designated fodrin) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin II, a neuronal cytoskeleton protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Fodrin / Alpha Spectrin II (SPTAN1) / NEAS (SPTAN1/3351), CF647 conjugate, 0.1mg/mL is BNC473351-100.
Fodrin / Alpha Spectrin II (SPTAN1) / NEAS (SPTAN1/3351), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Fodrin / Alpha Spectrin II (SPTAN1) / NEAS (SPTAN1/3351), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Fodrin / Alpha Spectrin II (SPTAN1) / NEAS (SPTAN1/3351), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Fodrin / Alpha Spectrin II (SPTAN1) / NEAS (SPTAN1/3351), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Fodrin / Alpha Spectrin II (SPTAN1) / NEAS (SPTAN1/3351), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b0061270361e1095cc/msds/bnc473351-100.pdf.
Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
