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Product details

CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL

Catalog number BNC403381-500

Price for BNC403381-500

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Size / count 1x 500 µL

About this product

Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF receptor superfamily which includes Fas antigen and CD40. TNF-R1 contains a cytoplasmic motif, termed the death domain , that has been found to be necessary for the transduction of the apoptotic signal. The death domain is also found in several other receptors, including Fas, DR2 (or TRUNDD), DR3 (death receptor 3), DR4 and DR5. TRUNDD, DR4 and DR5 are receptors for the apoptosis-inducing cytokine TRAIL. A non-death domain-containing receptor, designated decoy receptor (DcR1 or TRID), also specifically associates with TRAIL and may play a role in cellular resistance to apoptotic stimuli. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC403381-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death receptor 5 (DR5) ; p53 regulated DNA damage inducible cell death receptor (killer) ; TNF related apoptosis inducing ligand receptor 2 (TRICK2; Tumor necrosis factor receptor like protein ZTNFR9; Tumor necrosis factor receptor superfamily member 10B; ZTNFR9
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TNFRSF10B
Gene ID
8795
NCBI Gene ID
661668
UniProt
521456
Swiss Prot
521456
Host
Mouse
Species Reactivity
Human
Reactivity
CD262|DR5
Immunogen
Recombinant human DR5 protein fragment (around aa266-393) (exact sequence is proprietary)
Target Antigen
CD262 | DR5
Clonality
Monoclonal
Clone
DR5/3381
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Human colon cancer or endometrial tissue (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
48 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL?

The catalog number for CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL is BNC403381-500.

What sizes are available for CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL?

CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL in stock?

CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL?

CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL?

The safety data sheet for CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b8061270361e10bfd4/msds/bnc403381-500.pdf.

What is CD262 / DR5 (DR5/3381), CF640R conjugate, 0.1mg/mL used for?

Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF recepto

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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