CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL

Catalog number BNC473381-100

Price for BNC473381-100

Size / count 1x 100 µL

About this product

Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF receptor superfamily which includes Fas antigen and CD40. TNF-R1 contains a cytoplasmic motif, termed the death domain , that has been found to be necessary for the transduction of the apoptotic signal. The death domain is also found in several other receptors, including Fas, DR2 (or TRUNDD), DR3 (death receptor 3), DR4 and DR5. TRUNDD, DR4 and DR5 are receptors for the apoptosis-inducing cytokine TRAIL. A non-death domain-containing receptor, designated decoy receptor (DcR1 or TRID), also specifically associates with TRAIL and may play a role in cellular resistance to apoptotic stimuli. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC473381-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death receptor 5 (DR5) ; p53 regulated DNA damage inducible cell death receptor (killer) ; TNF related apoptosis inducing ligand receptor 2 (TRICK2; Tumor necrosis factor receptor like protein ZTNFR9; Tumor necrosis factor receptor superfamily member 10B; ZTNFR9
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TNFRSF10B
Gene ID: 8795
NCBI Gene ID: 661668
UniProt: 521456
Swiss Prot: 521456
Host: Mouse
Species Reactivity: Human
Reactivity: CD262|DR5
Immunogen: Recombinant human DR5 protein fragment (around aa266-393) (exact sequence is proprietary)
Target Antigen: CD262 | DR5
Clonality: Monoclonal
Clone: DR5/3381
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human colon cancer or endometrial tissue (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 48 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL?

The catalog number for CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL is BNC473381-100.

What sizes are available for CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL?

CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL in stock?

CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL?

CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100a36/msds/bnc473381-100.pdf.

What is CD262 / DR5 (DR5/3381), CF647 conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.