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Product details

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL

Catalog number BNC943398-500

Price for BNC943398-500

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Size / count 1x 500 µL

About this product

Recognizes a 33 kDa glycoprotein, identified as Nucleophosmin (NPM) . It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC943398-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
NO38; NPM; NPM1; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Nucleophosmin (nucleolar phosphoprotein B23 numatrin) ; Nucleophosmin; Nucleophosmin/nucleoplasmin family member 1; Numatrin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NPM1
Gene ID
4869
NCBI Gene ID
557550
UniProt
P06748
Swiss Prot
P06748
Host
Mouse
Species Reactivity
Human
Reactivity
Nucleophosmin
Immunogen
Recombinant human NPM1 protein fragment (aa185-287) (exact sequence is proprietary)
Target Antigen
Nucleophosmin
Clonality
Monoclonal
Clone
NPM1/3398
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
MCF-7, HeLa or A431 cells. Skin, Colon
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
33 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL?

The catalog number for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL is BNC943398-500.

What sizes are available for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL in stock?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e1006b4/msds/bnc943398-500.pdf.

What is Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF594 conjugate, 0.1mg/mL used for?

Recognizes a 33 kDa glycoprotein, identified as Nucleophosmin (NPM) . It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphopr

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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