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Product details

HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL

Catalog number BNCB3475-100

Price for BNCB3475-100

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Size / count 1x 100 µL

About this product

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six alpha and ten beta chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB3475-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HLA-DP; HLA-DQ; HLA-DR
Gene ID
3115; 3117; 3122
NCBI Gene ID
347270; 550475; 520048
UniProt
P04440; P01908; P01909; P01920; P01903
Swiss Prot
P04440; P01908; P01909; P01920; P01903
Host
Mouse
Species Reactivity
Human
Reactivity
HLA-Pan|MHCII
Immunogen
Non-T, non-B human acute lymphoblastic leukemia REH6 cells
Target Antigen
HLA-Pan | MHCII
Clonality
Recombinant Monoclonal
Clone
RHLA-Pan/3475
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified)
Positive Control
Raji cells. Tonsil or lymph node
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
33-35 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL?

The catalog number for HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL is BNCB3475-100.

What sizes are available for HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL?

HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL in stock?

HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL?

HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL?

The safety data sheet for HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100dc8/msds/bncb3475-100.pdf.

What is HLA-Pan (MHC II) (rHLA-Pan/3475), Biotin conjugate, 0.1mg/mL used for?

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

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