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Product details

HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL

Catalog number BNUB3475-100

Price for BNUB3475-100

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Size / count 1x 100 µL

About this product

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six alpha and ten beta chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB3475-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HLA-DP; HLA-DQ; HLA-DR
Gene ID
3115; 3117; 3122
NCBI Gene ID
347270; 550475; 520048
UniProt
P04440; P01908; P01909; P01920; P01903
Swiss Prot
P04440; P01908; P01909; P01920; P01903
Host
Mouse
Species Reactivity
Human
Reactivity
HLA-Pan|MHCII
Immunogen
Non-T, non-B human acute lymphoblastic leukemia REH6 cells
Target Antigen
HLA-Pan | MHCII
Clonality
Recombinant Monoclonal
Clone
RHLA-Pan/3475
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified)
Positive Control
Raji cells. Tonsil or lymph node
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
33-35 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL?

The catalog number for HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL is BNUB3475-100.

What sizes are available for HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL?

HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL in stock?

HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL?

HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL?

Estimated delivery time for HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL?

The safety data sheet for HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029f061270361e103434/msds/bnub3475-100.pdf.

What is HLA-Pan (MHC II) (rHLA-Pan/3475), 0.2mg/mL used for?

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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