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Product details

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL

Catalog number BNC883557-500

Price for BNC883557-500

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Size / count 1x 500 µL

About this product

This monoclonal antibody is specific to estrogen receptor alpha (ER alpha) and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e. g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC883557-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Estrogen Receptor alpha delta 4*5,6,7*/654 isoform; Estrogen Receptor alpha delta 4 49 isoform; Nuclear receptor subfamily 3 group A member 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ESR1
Gene ID
2099
NCBI Gene ID
208124
UniProt
P03372
Swiss Prot
P03372
Host
Mouse
Species Reactivity
Human
Reactivity
Estrogen Receptor, alpha
Immunogen
Recombinant fragment (around aa129-312) of human ESR1 protein (exact sequence is proprietary)
Target Antigen
Estrogen Receptor, alpha
Clonality
Monoclonal
Clone
ESR1/3557
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified)
Positive Control
MCF-7 cells (IF). Human breast or endometrial carcinoma (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
67 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL?

The catalog number for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL is BNC883557-500.

What sizes are available for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL in stock?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e10189f/msds/bnc883557-500.pdf.

What is Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), CF488A conjugate, 0.1mg/mL used for?

This monoclonal antibody is specific to estrogen receptor alpha (ER alpha) and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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