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Product details

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL

Catalog number BNUB3557-100

Price for BNUB3557-100

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Size / count 1x 100 µL

About this product

This monoclonal antibody is specific to estrogen receptor alpha (ER alpha) and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e. g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB3557-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Estrogen Receptor alpha delta 4*5,6,7*/654 isoform; Estrogen Receptor alpha delta 4 49 isoform; Nuclear receptor subfamily 3 group A member 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ESR1
Gene ID
2099
NCBI Gene ID
208124
UniProt
P03372
Swiss Prot
P03372
Host
Mouse
Species Reactivity
Human
Reactivity
Estrogen Receptor, alpha
Immunogen
Recombinant fragment (around aa129-312) of human ESR1 protein (exact sequence is proprietary)
Target Antigen
Estrogen Receptor, alpha
Clonality
Monoclonal
Clone
ESR1/3557
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified)
Positive Control
MCF-7 cells (IF). Human breast or endometrial carcinoma (IHC).
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
67 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL?

The catalog number for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL is BNUB3557-100.

What sizes are available for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL in stock?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL?

Estimated delivery time for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL?

The safety data sheet for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a5061270361e105671/msds/bnub3557-100.pdf.

What is Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/3557), 0.2mg/mL used for?

This monoclonal antibody is specific to estrogen receptor alpha (ER alpha) and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

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