CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL

Catalog number BNC043588-100

Price for BNC043588-100

Size / count 1x 100 µL

About this product

This MAb specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45 kDa, containing 8 kDa of N-glycoside-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro) . CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC043588-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ALPS1A; Apoptosis APO1 antigen 1; Apoptosis-mediating surface antigen FAS; APT1; Delta Fas; Fas AMA; Fas cell surface death receptor; FAS1; FASL receptor; FASLG receptor; FASTM; Surface antigen APO1; Tumor necrosis factor receptor superfamily member 6 (TNFRSF6)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FAS
Gene ID: 355
NCBI Gene ID: 244139
UniProt: P25445
Swiss Prot: P25445
Host: Mouse
Species Reactivity: Human
Reactivity: CD95|FAS|TNFRSF6
Immunogen: Recombinant fragment (around aa26-96) of human CD95 (FAS) protein (exact sequence is proprietary)
Target Antigen: CD95 | FAS | TNFRSF6
Clonality: Monoclonal
Clone: FAS/3588
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: MCF-7 cells (IF/FACS). Human hepatocellular or bladder carcinoma (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 38-50 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL?

The catalog number for CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL is BNC043588-100.

What sizes are available for CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL?

CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL in stock?

CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL?

CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL?

The safety data sheet for CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ad061270361e108386/msds/bnc043588-100.pdf.

What is CD95 / FAS / TNFRSF6 (FAS/3588), CF405S conjugate, 0.1mg/mL used for?

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.