CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL

Catalog number BNC883588-500

Price for BNC883588-500

Size / count 1x 500 µL

About this product

This MAb specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45 kDa, containing 8 kDa of N-glycoside-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro) . CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC883588-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ALPS1A; Apoptosis APO1 antigen 1; Apoptosis-mediating surface antigen FAS; APT1; Delta Fas; Fas AMA; Fas cell surface death receptor; FAS1; FASL receptor; FASLG receptor; FASTM; Surface antigen APO1; Tumor necrosis factor receptor superfamily member 6 (TNFRSF6)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FAS
Gene ID: 355
NCBI Gene ID: 244139
UniProt: P25445
Swiss Prot: P25445
Host: Mouse
Species Reactivity: Human
Reactivity: CD95|FAS|TNFRSF6
Immunogen: Recombinant fragment (around aa26-96) of human CD95 (FAS) protein (exact sequence is proprietary)
Target Antigen: CD95 | FAS | TNFRSF6
Clonality: Monoclonal
Clone: FAS/3588
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: MCF-7 cells (IF/FACS). Human hepatocellular or bladder carcinoma (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 38-50 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL?

The catalog number for CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL is BNC883588-500.

What sizes are available for CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL?

CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL in stock?

CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL?

CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL?

The safety data sheet for CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102cdf/msds/bnc883588-500.pdf.

What is CD95 / FAS / TNFRSF6 (FAS/3588), CF488A conjugate, 0.1mg/mL used for?

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.