CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL

Catalog number BNC043592-500

Price for BNC043592-500

Size / count 1x 500 µL

About this product

CD23 (FCE2) is a type II integral membrane glycoprotein that is expressed on mature B cells, monocytes, eosinophils, platelets and dendritic cells. CD23 is a low affinity IgE receptor that mediates IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. CD23 associates as an oligomer where cooperative binding of at least two lectin domains is required for high affinity IgE binding to CD23. It may play a role in antigen presentation by B cells by interacting with CD40. CD23 has been shown to be associated with the Fyn tyrosine kinase. The truncated molecule can be secreted, then function as a potent mitogenic growth factor. CD23 is expressed on a subpopulation of peripheral blood cells, B-lymphocytes and on EBV transformed B lymphoblastoid cell lines. CD23 is also detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some cases on centroblastic/centrocytic lymphoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC043592-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BLAST-2; C-type lectin domain family 4; member J; CD23; Fc fragment of IgE low affinity II receptor; Fc-epsilon-RII; FCER2; FCER2A; FceRII; IgE-binding factor (IGEBF) ; Immunoglobulin E receptor; low affinity II; Lymphocyte IgE receptor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FCER2
Gene ID: 2208
NCBI Gene ID: 465778
UniProt: P06734
Swiss Prot: P06734
Host: Mouse
Species Reactivity: Human
Reactivity: CD23
Immunogen: Recombinant fragment (around aa 48-321) of human FCER2/CD23 protein (exact sequence is proprietary)
Target Antigen: CD23
Clonality: Monoclonal
Clone: FCER2/3592
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human lymph node or tonsil (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 37 kDa (soluble form) ; 45 kDa (membrane-bound form)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL?

The catalog number for CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL is BNC043592-500.

What sizes are available for CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL?

CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL in stock?

CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL?

CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL?

The safety data sheet for CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b1061270361e109cdc/msds/bnc043592-500.pdf.

What is CD23 (Fc Epsilon RII) (FCER2/3592), CF405S conjugate, 0.1mg/mL used for?

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.