CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL

Catalog number BNC473592-100

Price for BNC473592-100

Size / count 1x 100 µL

About this product

CD23 (FCE2) is a type II integral membrane glycoprotein that is expressed on mature B cells, monocytes, eosinophils, platelets and dendritic cells. CD23 is a low affinity IgE receptor that mediates IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. CD23 associates as an oligomer where cooperative binding of at least two lectin domains is required for high affinity IgE binding to CD23. It may play a role in antigen presentation by B cells by interacting with CD40. CD23 has been shown to be associated with the Fyn tyrosine kinase. The truncated molecule can be secreted, then function as a potent mitogenic growth factor. CD23 is expressed on a subpopulation of peripheral blood cells, B-lymphocytes and on EBV transformed B lymphoblastoid cell lines. CD23 is also detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some cases on centroblastic/centrocytic lymphoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC473592-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BLAST-2; C-type lectin domain family 4; member J; CD23; Fc fragment of IgE low affinity II receptor; Fc-epsilon-RII; FCER2; FCER2A; FceRII; IgE-binding factor (IGEBF) ; Immunoglobulin E receptor; low affinity II; Lymphocyte IgE receptor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FCER2
Gene ID: 2208
NCBI Gene ID: 465778
UniProt: P06734
Swiss Prot: P06734
Host: Mouse
Species Reactivity: Human
Reactivity: CD23
Immunogen: Recombinant fragment (around aa 48-321) of human FCER2/CD23 protein (exact sequence is proprietary)
Target Antigen: CD23
Clonality: Monoclonal
Clone: FCER2/3592
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human lymph node or tonsil (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 37 kDa (soluble form) ; 45 kDa (membrane-bound form)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL?

The catalog number for CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL is BNC473592-100.

What sizes are available for CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL?

CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL in stock?

CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL?

CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a9061270361e106fc9/msds/bnc473592-100.pdf.

What is CD23 (Fc Epsilon RII) (FCER2/3592), CF647 conjugate, 0.1mg/mL used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.