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Product details
Catalog number BNC043608-500
Price for BNC043608-500
Size / count 1x 500 µL
Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2 -dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG) . BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF405S conjugate, 0.1mg/mL is BNC043608-500.
Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a9061270361e106d27/msds/bnc043608-500.pdf.
Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.
