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Product details

Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL

Catalog number BNC943608-100

Price for BNC943608-100

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Size / count 1x 100 µL

About this product

Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2 -dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG) . BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC943608-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
C-type lectin domain family 4 member K; CD207; CLEC4K; Langerhans cell specific c type lectin; Langerin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD207
Gene ID
50489
NCBI Gene ID
199731
UniProt
Q9UJ71
Swiss Prot
Q9UJ71
Host
Mouse
Species Reactivity
Human
Reactivity
CD207|Langerin
Immunogen
Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
Target Antigen
CD207 | Langerin
Clonality
Recombinant Monoclonal
Clone
RLGRN/1821
Type
Primary
Source
Animal
Origin
Animal
Positive Control
HeLa or A549 cells (WB).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
48 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL?

The catalog number for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL is BNC943608-100.

What sizes are available for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL?

Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL in stock?

Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL?

Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029e061270361e10307e/msds/bnc943608-100.pdf.

What is Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), CF594 conjugate, 0.1mg/mL used for?

Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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